Dipeptidyl peptidase 4 (DPP-4) inhibitors (also known as gliptins) are a class of oral diabetes medicines that lower high blood glucose levels and may be used in the treatment of type 2 diabetes. DPP-4 inhibitors block the enzyme dipeptidyl peptidase-4 (DPP-4).
Mode of action
- Increase incretin levels.
- Incretins are a group of metabolic hormones, released after eating, that decrease blood glucose levels by augmenting the secretion of insulin. This is a blood glucose-dependent mechanism.